First of all, there were medical specialists involved in the development process throughout the whole year. The main one was Marko Mikša, MD. He has experience in Plastic, Reconstructive, Aesthetic Surgery, and Burns (including Carpal Tunnel surgeries). You can check his LinkedIn profile here. Other consultants were several physicians trained in occupational medicine.
One of the studies that we took into account was conducted by Harvard School of Public Health, Kettering University and Northeastern University and showed that raised palm support was associated with less wrist extension and lower applied forces to the mouse pad. Participants also reported less musculoskeletal discomfort when using a support. You can read more here.
Furthermore, let’s compare Carpio with other solutions that you’re probably familiar with, gel wrist pads for example. Well, in most cases, those don’t provide any significant ergonomic benefit and usually increase the risk by:
Applying the pressure to the underside of the wrist, or carpal tunnel to be more precise, and compressing the tissues, slowing down blood supply...
Fixing your wrist position, which causes additional stress for your wrist as you are forced to move the mouse by rotating/flexing your wrist instead of using your whole arm and shoulder (larger, stronger muscles)
And that's why Carpio reinforces that pressure from the wrist to the lower palm (thenar and hypothenar part), so actually, it's a palm rest rather than a wrist rest, and lifts your wrist for about a centimeter to reduce the harmful extension. Also, it moves/glides together with your hand and enables the arm and shoulder motion.